Fucoidan Powder 85%

What is Fucoidan Powder?

Fucoidan is a sulfate-rich polysaccharide. It is primarily a water-soluble fiber and is chemically composed of a polysaccharide of fucose sulfate. Fucoidan differs from other plant polysaccharides in that it is rich in sulfate groups and therefore has superior disease-fighting properties. It is mainly found in the extracellular mesenchyme of algae such as brown algae and green algae and is also one of the constituent parts of some marine invertebrates (e.g. sea urchins and sea cucumbers).

This polysaccharide was first isolated from marine brown algae in 1913 AD by Dr Kylin, who named it ‘fucoxanthin’ and it is now known by the common name fucoidan, when he was analyzing the reasons for the low incidence of cancer in Okinawa, Japan. Numerous animal and in vitro studies have found that fucoidan has a wide range of biological activities, including antibacterial, antioxidant, anticoagulant, antiviral, antitumor, and anti-inflammatory.

Green Spring supplies Fucoidan Powder 85%, which is made from the algal bodies of kelp or wakame from China's high quality sea area, through the process of aqueous extraction, anhydrous ethanol precipitation, dehydration, drying, etc. It is of high purity and stable performance. Green Spring also supplies food-grade fucoidan in powder form, which can be used in a variety of dosage forms, such as solid beverages, tablets, capsules, or added to some functional foods, such as pressed candies, coffee, meal replacements, enzyme powders, and so on.

Founded in 2000, Green Spring is a leading biotechnology company in China, that has been committed to researching and providing natural, safe, and organic plant extracts. Green Spring has obtained Halal, Kosher, COSMOS, BRC, IFS, FDA, ISO9001, ISO22000 and many other certifications. Our products are manufactured according to the highest international standards, such as EC396, 2023/915, and the highest solvent residue standards. 

Specification:  

Regulation:

It conforms to EU regulations.

Benefits:

Enhancement of Immunity

Fucoidan can enhance the body's immunity, increase the expression of anti-inflammatory factors and receptors, produce antioxidant and anti-inflammatory effects, and regulate the immune response through a variety of pathways, thus inhibiting its inflammatory response. The results of antioxidant experiments show that it can effectively scavenge ROS in Vero cells, enhance cell survival, and inhibit apoptosis.

Meanwhile, it can effectively alleviate AAPH-induced damage in zebrafish, such as enhancing embryo survival, scavenging ROS, and inhibiting lipid peroxidation. The results of anti-light aging experiments showed that it could effectively alleviate UVB-induced HaCaT cell damage, such as scavenging intracellular ROS, inhibiting apoptosis, and enhancing cell survival; meanwhile, it could effectively improve UVB-induced oxidative damage and inflammatory response in zebrafish.

Tumour Suppression

Numerous studies have shown that fucoidan can inhibit cancer by enhancing immune system function. This is because after fucoidan enters the gut, it is recognized by immune cells to produce signals that activate the immune system, creating activation of NK cells, B cells, and T cells, resulting in the production of antibodies with the ability to bind to cancer cells and T cells with the ability to kill cancer cells, specifically killing cancer cells and inhibiting their growth.

The researchers first demonstrated the effect of fucoidan at the cellular level using experimental liver cancer cells, HepG2-SR cells. The effects of fucoidan on the cell cycle and apoptosis-related proteins were also observed. The migration of cancer cells was also shown to be greatly inhibited by fucoidan in invasion and scratch assays.

Conservation of Gastric Mucosa

In 2015, Professor T. Sweeney's team at the University College Dublin, Ireland, took piglets suffering from chronic colitis as a model and fed fucoidan to the piglets every day for 2 months to observe the condition of colitis and the intestinal flora of the piglets. The experimental results showed that the piglets receiving fucoidan had significant relief of diarrhoea and effective weight gain, and at the same time, the analysis of the intestinal flora and inflammatory factors in the piglets' intestines revealed that fucoidan could improve the intestinal flora and effectively reduce the production of the inflammatory factor interleukin-6.

In 2017, a team of researchers from Professor Ryuji Takeda at Kansai University of Welfare Sciences in Japan conducted a study in which they divided 30 patients with constipation into two groups, with the test group taking 1 gram of fucoidan per day and the control group taking a placebo. Two months after the test found that the test group taking fucoidan weekly bowel movement days from the original average of 2.7 days to 4.6 days, the volume and softness of the bowel movement have increased significantly, the experiment verified that fucoidan can effectively improve constipation.

Regulates the Bowel

Fucoidan has also been shown to bi-directionally regulate intestinal effects such as improving constipation and inflammation.A 2017 Japanese study showed that constipated patients who took 1 gram of fucoidan per day had an increase in the number of days of bowel movements per week from 2.7 to 4.6 after two months, and had improved bowel size and softness. Previously, a series of in vitro and animal studies have shown effective inhibition of key inflammatory enzymes expressed in the gastrointestinal tract, slowing the clinical symptoms of ulcerative colitis. Recently, a recent clinical study has further confirmed the benefits of fucoidan on gut health in athletes, providing optimal support for athletic performance.

Benefits Cardiovascular Health

Fucoidan attenuates atherosclerotic damage by reducing leukocyte and platelet adhesion on dysfunctional or damaged endothelium and inhibits thrombin production. It also inhibits free radical processes, lowers cholesterol levels, and inhibits lipid accumulation. In addition, fucoidan reduces thrombin production in the microvascular system and promotes angiogenesis by recruiting endothelial progenitor cells, which may attenuate myocardial infarction and stimulate the regeneration of blood vessels in ischaemic areas.

Applications:

For Healthcare Products:

Fucoidan has a variety of pharmacological activities, showing high medicinal value in antioxidant, anti-tumour, hypoglycaemic and neuroprotective aspects. As early as 2003, China approved a fucoidan-based traditional Chinese medicine product ‘Haikun Renxi Capsule’ for the treatment of chronic renal failure. In recent years, fucoidan powder has gradually penetrated into the food field with its remarkable health care value, and many regions such as the United States and the European Union have approved the application of fucoidan in the food field, and the U.S. FDA has also recognised it as GRAS.