Natural Vitamin K2 MK7 Powder 1.5%

What is Natural Vitamin K2 MK7 Powder?

Vitamin K2, also known as MK-7 (Menaquinone-7), is a fat-soluble vitamin K derivative. It is one of the more active forms of the vitamin K family and has important physiological functions. On 1 July 2017, the United States Pharmacopoeia Committee concluded that vitamin K2MK-7 has superior bioavailability.MK-7 is a vitamin K2 ( Methylnaphthoquinone) of 7 isoprenoid units forming a side chain with the molecular formula C46H64O2 and the molecular weight of 649. 00.

Vitamin K2 MK7 has higher bioavailability, longer half-life, and greater anti-osteoporotic activity than MK-4. Vitamin MK7 is the best form of vitamin K2 and natto is the best source of Vitamin K2 MK7. It is important to note that only the "trans" configuration of MK7 is biologically active.

Vitamin K2 MK7 promotes the carboxylation of extrahepatic vitamin K2-dependent protein (VK2DP), osteocalcin (OC), and matrix Gla protein (MGP), which is capable of combating osteoporosis.

On 31 March 2020, the journal Nutrients published a review of the effects of Vitamin K2 MK7 on bone mass and bone strength by Toshiro Sato and others. Conclusion: Compared with Vitamin K2 MK4, Vitamin K2 MK7 has a higher bioavailability and longer half-life, and is more likely to increase bone density and improve bone quality, bone strength, and collagen production.

Green Spring Technology supplies Natural Vitamin K2 MK7 Powder 1.5%, which is produced by a pure strain of Nattokinella, through modern biotechnology induced output of highly active strains of Vitamin K2 MK7, with better bioactivity and high bioavailability. No organic solvent extraction, physical separation and concentration technology, no secondary pollution, no preservatives, no additives, no chemical solvents, no synthesis, stable and long-lasting activity.

Specification:

Regulations:

It conforms to EU regulations.

Benefits:

Anti-Osteoporosis

Vitamin K2 MK7 powder promotes bone formation and reduces bone resorption by activating osteocalcin, stimulating osteoblast differentiation, regulating extracellular matrix mineralization, and inhibiting osteoclastogenesis, thereby preventing osteoporosis. Moreover, animal studies and clinical trials over the years have proved that Vitamin K2 MK7 has the health benefits of promoting bone health and preventing osteoporosis. Therefore, MK7 supplements have been approved for marketing in China, and experts recommend that clinicians use supplements containing Vitamin K2 MK7 powder to prevent and treat osteoporosis.

Improving Dental Health

One of the major regulatory proteins for dental health is osteocalcin, a protein essential for bone metabolism that can be activated by vitamin K2. Dentin is the calcified tissue underneath the enamel on teeth, and osteocalcin triggers a mechanism that stimulates the growth of new dentin.

Helps Fight Cancer

Vitamin K2 MK7 can inhibit tumour growth by negatively regulating tyrosine kinase and phosphodiesterase activities associated with cell carcinogenesis, as well as modulating regulatory factors associated with cell proliferation, ultimately leading to cell cycle inhibition in tumour cells.

Improve Diabetes

Vitamin K2 MK7 powder upregulates the insulin gene, promotes pancreatic beta cells, and releases insulin, which can improve the body's metabolic levels and help diabetics recover.

Promote Calcium Absorption

Vitamin K2 contributes to bone development or bone density by carboxylating glutamic acid residues in osteocalcin to gamma-carboxyglutamic acid residues, which activates osteocalcin to form "calcium claws" that bind to hydroxyapatite and promote bone mineral salt deposition. The researchers conducted a double-blind controlled trial of vitamin K2 MK7 powder supplementation for 8 weeks in 55 children and adolescents, measuring serum levels of uncarboxylated osteocalcin (ucOC), carboxylated osteocalcin (cOC), and MK7 for calcium absorption.

The results show that moderate supplementation of Vitamin K2 MK7 powder in healthy adolescent children can increase the concentration of MK7 and increase osteocalcin carboxylation; ucOC is secreted by osteoblasts, and vitamin K2 converts ucOC to cOC, which further forms a calcium claw that leads calcium into the bone and promotes calcium absorption.

Inhibits Vascular Calcification

Vitamin K2 reduces the risk of cardiovascular problems by activating Matrix Gla Protein (MGP), which inhibits the calcification of calcium ions in the arteries.

Researchers in Rotterdam, the Netherlands, conducted a 10-year study involving more than 4,800 people (≥55 years of age) to investigate whether dietary intake of vitamin K2 was associated with cardiovascular problems such as aortic calcification. The results showed that vitamin K2 intake led to a reduction in the relative risk of cardiovascular problems and that subjects who consumed more than 32.7 μg of vitamin K2 per day had a 50 percent reduction in the risk of aortic calcification compared to those who consumed lower doses.

Applications:

For Health Products:

In the international nutraceutical market, Vitamin K2 powder products include Vitamin K2 (MK-4) and Vitamin K2 MK7 powder, of which:Vitamin K2 MK4 is synthetic and has a short half-life, while Vitamin K2 MK 7 powder is mostly produced by fermentation and has a longer period of action. Natural Vitamin K2 MK7 Powder has been widely used as a nutraceutical additive.