Melatonin Raw Powder

What is Melatonin Raw Powder?

Melatonin, scientific name N-acetyl-5-methoxytryptamine. It is a lipophilic indoleamine, produced by the pineal gland of the brain, and mainly acts on the supraoptic nucleus of the hypothalamus, regulating the sleep-wake cycle by activating melatonin receptors. Studies have shown that melatonin can improve sleep, enhance immunity, slow down aging, and even inhibit the formation of tumors.

Green Spring Technology supplies Melatonin Raw Powder, its purity is higher than 99.5%, and its microorganisms, heavy metals, and solvent residues follow the U.S. Pharmacopoeia, Japanese Pharmacopoeia and European Pharmacopoeia.

Founded in 2000, Green Spring Technology is a leading biotechnology company in China. It is dedicated to researching and supplying high quality plant extracts, nutraceutical ingredients, and food ingredients. It has 8 certificates and 7 patents, and its products are sold in more than 62 countries, serving more than 2,450 customers.

Specification: 

Regulation:

It conforms to EU regulations.

Benefits:

Improving Sleep

Studies have found that melatonin use can alleviate insomnia from different causes and can prolong the relatively short period of Rapid Eye Movement (REM) sleep. The Rapid Eye Movement sleep period (REM sleep) is a state that humans and other mammals experience during sleep. During REM sleep, our eyes rapidly scan our surroundings while our brain activity is very active. This stage usually occurs during the second half of a full sleep cycle and can last anywhere from a few minutes to several hours.

REM sleep is considered a critical recovery and recharging time, helping to strengthen memory, improve emotional stability, and boost the body's repair and metabolism. Therefore, extending the duration of REM sleep can help improve the quality of your sleep and leave you feeling more refreshed and rejuvenated.

Anti-tumor

Vijayalaxmi et al. (1995) found that melatonin had a significant protective effect against chromosome damage in human peripheral lymphocytes caused by gamma rays of 137Cs (150 cGy) in a dose-effect relationship, and antagonized physical and chemical mutagenicity and carcinogenicity produced by free radicals.

In vitro tests showed that melatonin also had a protective effect against autoclave C-induced mutagenicity. Melatonin reduces the formation of DNA adducts induced by chemical carcinogens (safrole) and prevents DNA damage. Yan et al. studied the antitumor effect of melatonin on H22 hepatocellular carcinoma mice and found that it could inhibit tumor growth and prolong the survival time of hormonal mice, and there was obvious synergy with IL-2.

Regulation of the Central Nervous System

A large number of clinical and experimental studies have shown that melatonin, as an endogenous neuroendocrine hormone, has direct and indirect physiological regulation of the central nervous system, has a therapeutic effect on sleep disorders, depression and psychiatric disorders, and has a protective effect on nerve cells. For example, melatonin has a sedative effect, but also treats depression and psychosis, can protect the nerves, can be analgesic, regulates the release of hormones from the hypothalamus, and so on.

Benefits for Bone Health

A systematic analysis suggests that oral melatonin increases osteocalcin. The mechanism behind this may be related to melatonin's ability to prevent bone loss by affecting osteoblast and osteoclast formation through molecules such as the MT2 melatonin receptor, MEK1/2, and MEK5. Targeting peri- and postmenopausal women, melatonin may positively contribute to bone health.

Regulation of the Immune System

Melatonin, as a neuroendocrine hormone, has a supplementary regulatory effect on the immune system. It can enhance the body's immune function and improve the body's resistance to infectious diseases. At the same time, melatonin also promotes the regeneration of pineal function, consolidates and maintains the functions of all major organs and systems of the body, and strengthens the overall health of the body.

Applications:

In Pharmaceutical:

Melatonin, as a monomer component of drugs with various biological activities, has a broad research prospect in the field of medicine. Due to its strong hepatic first pass effect and low oral bioavailability, gelatin microspheres for nasal mucosal delivery have been developed to avoid the first pass effect and at the same time improve the bioavailability of the drug.

For Healthcare Products:

Melatonin can enable a person to quickly enter a deep sleep state, reduce the number of awakenings during sleep, and improve the quality of sleep. Melatonin is an endogenous hormone that scavenges free radicals, and antioxidants and protects cellular integrity, so taking melatonin can accelerate the body's metabolism and have anti-aging effects. Studies have shown that melatonin can regulate women's ovulation, regulate mood problems and sleep problems caused by endocrine disorders during menopause. Melatonin powder, as a raw material for health products, has been used in other functional health products such as improving sleep.