Cistanche Tubulosa Extract Powder

What is Cistanche Tubulosa Extract Powder?

Cistanche Extract Powder is a powdered active ingredient extracted from the dried fleshy stems with scaly leaves of Cistanche tubulosa (Schenk) Wight of the family Ledebouriaceae. The main active ingredients of Cistanche tubulosa extract are pinacoside, trichoside, and total phenylethanol glycosides. It mainly contains alkaloids and phenylethanol glycosides, which have anti-aging and antioxidant effects.

Medical research has found that the active ingredients contained in Cistanchis extracts can promote the regeneration and metabolism of human cells, enhance the immune regulation ability, and have obvious anti-cancer, anti-virus, and delayed aging effects. In recent years, good results have been achieved in the treatment of prostate enlargement and hyperplasia, leukemia, diabetes, asthma, and premature ejaculation with Cistanchis.

Green Spring Technology supplies superior quality Cistanche Tubulosa Extract Powder, its main active ingredients are Verbascoside and Echinacoside, brownish yellow fine powder. It is stable and soluble, has low water content, and can be stored in a cool place for 24 months without adding preservatives. This Cistanche Tubulosa Extract Powder is a high-quality plant extract raw material used to process various nutraceuticals.

Green Spring Technology is a leading biotechnology company in China, it was founded in 2000 and is dedicated to providing natural, safe, and organic plant extracts to our customers. Lvquan has obtained many certificates such as Halal, Kosher, COSMOS, BRC, IFS, FDA, ISO9001, ISO22000, etc. Green Spring products comply with EU EC396, EU 2023/915 standards, and the highest standards. The products comply with EU EC396, EU 2023/915, and the highest solvent residue standards. 

Specification: 

Regulation:

It conforms to EU regulations.

Benefits:

Delaying Aging

Zhu et al. investigated the anti-aging mechanism of Cistanchis and found that the pinealoside in Cistanchis could down-regulate the expression of p53, and thus inhibit the aging of human fibroblasts. Xu et al. investigated the effects of Cistanchis on liver mitochondria explored the anti-aging mechanism of Cistanchis, and found that different components of Cistanchis could increase the antioxidant capacity of the liver, reduce the oxidative damage of mitochondria in hepatocytes, and promote energy metabolism, which can achieve the effect of delaying the aging of the liver. Zheng et al. found that dietary supplementation with Cistanchis could significantly slow down the aging process of aged SAM-P8 mice in animal models. In an animal model, Zheng et al.

These studies suggest that Cistanchis can delay aging. Phenylethanol glycosides (PEGs) are the most reported compounds in Cistanchis. Phenylethanol glycosides (PEG) were found to have strong antioxidant activity by Wu et al. Guo et al. showed that Cistanchis polysaccharides also have high antioxidant activity. Han Haixia et al. found that Cistanchis extract can scavenge DPPH radicals, ABTS radicals, and hydroxyl radicals, and reduce iron ions, so Cistanchis extract has strong antioxidant activity.

Relieve Physical Fatigue

Cistanchis and Cistanchis extracts have been found to reduce physical fatigue. Yan Lei et al. found that the injection of 100 mg/kg of Cistanchiakis polysaccharide (CDP) could significantly prolong the weight-bearing swimming time, reduce the serum (BUN) and lactic acid (LA) content, increase the content of hepatic glycogen and myo-glycogen, and increase the activity level of superoxide dismutase (SOD) and glutathione peroxidase (GSH-PX) in the liver tissues of aged mice, and reduce the content of malondialdehyde (MDA). It also increased the activity levels of superoxide dismutase (SOD) and glutathione peroxidase (GSH-PX) in the liver tissues of aging mice, and decreased the content of malondialdehyde (MDA).

Memory Enhancement

Feng Duo et al. found that Cistanchis and its active ingredients can reduce brain damage, enhance memory, and prevent Alzheimer's disease. Xing Haiyan et al. showed that in the water maze experiment, the escape latency and the first arrival time of mice in the gavage group of Cistanchiakis were significantly shortened, and the number of times they crossed the station was significantly increased. Cistanchis polysaccharides had a significant protective effect on aging nerve cells and improved the learning memory ability of mice in the aging model.

Acteoside, a phenylethanol glycoside active substance in Cistanchis sinensis, was found to significantly increase neurons and Nissl in the hippocampus of mice treated with certain doses of acteoside (60 and 120 mg/kg/d) in an AD mouse model. Nitric oxide content, nitric oxide synthase activity, and caspase-3 protein expression were reduced compared with the AD model group, suggesting that acetonide, an active substance of Cistanchis sinensis, has the function of improving learning and memory.

Regulating Immunity

In Zheng et al.'s study, the MTT assay was used to observe the regulatory effect of Cistanche deserticola polysaccharides (CDPS) on the inhibition of mouse thymic lymphocyte proliferation by ISO DEX TNF - β in vitro. High quality concentrations (100 μ g/mL) of CDPS significantly promoted the increase of Ca2+ion concentration in mouse thymic cells, revealing the immune activity of CDPS and the mechanism of its in vitro immune regulation.

Laxative

Wang Li-wei et al. found that Cistanchis dietary fiber has good laxative function, compared with the model group, the time of the first black stool discharge was shortened and the number of 6-h stools increased in all dose groups of Cistanchis dietary fiber mice; among them, the time of the first black stool discharge and the number of 6-h stools in the high-dose group of mice were significantly different from that in the model group.

Jia et al. demonstrated that Cistanchniches active substance (ECH) could improve the repair of mucosal tissue by stimulating the proliferation of intestinal epithelial cells and preventing cell death by regulating TGFβ, thus improving the repair of irritable bowel syndrome. Jia et al. showed that the active substance of Cistanchis sinensis (ECH) could treat irritable bowel syndrome or constipation by stimulating the proliferation of intestinal epithelial cells and preventing cell death through the up-regulation of TGF-β, thus improving the repair of mucosal tissues. 

Applications:

For Healthcare Products:

Cistanchis Extract can enhance human immunity, improve male sexual function, promote blood circulation, relieve fatigue, and so on. Cistanchis extract is also used to treat male impotence, premature ejaculation, prostatitis, and other diseases. Cistanchis Extract powder is widely used to make health care products, especially male health care products.

In Cosmetics:

Cistanchis has various effects such as whitening, anti-aging, sunscreen, moisturizing, etc. It has been used in cosmetics. Cosmetics containing Cistanchis tubulosa extract can enhance skin elasticity, reduce skin melanin content, and improve skin brightness. However, the research on the active ingredients and mechanism of action of Cistanchis is still insufficient.

In the Food Field:

Cistanchis extract can be used to make alcohol, such as Cistanchis wine. Cistanchis extract can not only add flavor to food but also enhance the nutritional value of food.