Melatonin Powder 99%

What is Melatonin Powder 99%?

Melatonin (N-acetyl-5-methoxytryptamine, MT), also known as pinealotropin, is a neurohormone widely distributed in higher organisms. It belongs to the indole group of hormones and was first successfully extracted from the pineal gland of cattle in 1958 by Lerner, a professor of dermatology at Yale University.

Numerous experimental studies have shown that melatonin can regulate the biological clock and re-establish biorhythms in the body. It stabilizes the rhythm of the body's internal clock, allowing it to better adapt to the daily routine. Therefore, melatonin has an important role to play in the disruption of the biological cycle caused by insomnia problems.

Melatonin Powder is a white crystalline powder with the molecular formula C13H16N2O2 and a purity usually greater than 99%.

Green Spring Technology supplies Melatonin Powder 99%, its powder is loose, with no lumps, and no impurities visible to the naked eye, through the ID test, heavy metals, solvent residues, microorganisms, and PAHS are in line with Pharmacopoeia standards.

Green Spring Technology is a leading biotechnology company in China, which was founded in 2000 and has been supplying natural food ingredients, nutraceutical ingredients and cosmetic ingredients. Green Spring has obtained many certifications such as Halal, Kosher, COSMOS, BRC, IFS, FDA, ISO9001, ISO22000, and so on. Its products fulfill the highest standards in the industry and comply with EU EC396, EU 2023/915 and the highest solvent residue standards. 

Specification: 

Regulation:

It conforms to EU regulations.

Benefits:

Improved Sleep

Studies have shown that ingesting melatonin results in a decrease in oral temperature, significantly shorter time to fall asleep, significantly longer sleep duration, decreased energy, and increased fatigue. In cases of insomnia due to melatonin deficiency, taking melatonin will shorten the time it takes to fall asleep, allowing a person to fall asleep quickly. It also prolongs deep sleep. However, if the sleep problem is not caused by the lack of melatonin in the body but by other reasons, such as bad moods, then melatonin supplementation will not improve the sleep problem.

Immunomodulation

Melatonin antagonizes the effects of stress immunosuppression in mice induced by psychogenic factors (acute anxiety), as well as prevents paralysis and death resulting from acute stress induced by infectious factors (sublethal dose of cerebral cardiomyopathy virus). Yan et al. investigated the regulatory effects of melatonin on immunity in H22 hepatocellular carcinoma mice and found that it could increase the CD4+CD8+ value in loaded mice, synergize with IL-2 to increase the number of peripheral blood lymphocytes and eosinophils, enhance the activity of splenocytes NK and LAK, and promote the induction of IL-2.

They also studied the regulatory effect of melatonin on macrophage function in H22 hepatocellular carcinoma mice and found that the killing activity of macrophages and the induction of IL-1 increased significantly on average after the injection, suggesting selective regulation of macrophage function. Kathleen et al. (1994) found that melatonin has the function of activating human monocytes, inducing their cytotoxicity and IL-1 secretion. Functions.

May Improve Menopausal Syndrome

Most clinical studies confirm that oral melatonin improves menopausal symptoms. Menopausal women who took 3mg of melatonin daily for 6 months showed significant improvement in physical symptoms of menopause and could eliminate symptoms of menopause-related depression, possibly related to melatonin supplementation improving menopausal neurological disorders and thyroid function.

Increase Bone Density

At this stage, it is believed that melatonin can regulate bone metabolism by activating MT2 receptors, regulating bone metabolism indexes, and antioxidants, regulating bone marrow mesenchymal stem cells, etc. It can also inhibit osteoblastic differentiation by down-regulating nuclear factors, receptor-activating factor ligands, and up-regulating calcitonin secretion. A large number of animal and human experiments have also proved that melatonin can change bone microstructure, regulate bone metabolic indexes, and increase bone density.

May Benefit Menopause Syndrome Blood Sugar Metabolism

Menopausal symptoms are associated with fluctuations in blood glucose. The study investigated placebo or melatonin given to normoglycemic menopausal women randomized in a double-blind fashion, followed 45 min later by an oral glucose tolerance test (75g OGTT), and found that the administration of 1 mg melatonin to menopausal women reduced glucose tolerance and insulin sensitivity.

Applications:

For Healthcare Products:

In the field of health products, melatonin powder is widely used to improve sleep, regulate the biological clock, antioxidants, and so on. Various health products containing melatonin such as melatonin soft capsules, melatonin tablets and other products are favored by consumers.

In Cosmetics:

In the cosmetic field, melatonin powder is widely used in skin care products and color cosmetics for its antioxidant and sleep-improving effects on beauty and well-being.

In Pharmaceutical:

Melatonin can also be used to relieve symptoms of insomnia, jet lag adjustment, and depression.