Wheat Germ Extract Spermidine Powder

What is Wheat Germ Extract Spermidine Powder?

Spermidine, also known as spermidine trihydrochloride, is a naturally occurring aliphatic polyamine compound found in living organisms, ribosomes, and living tissues. It is excellent in anti-inflammatory, and antioxidant, enhancing mitochondrial metabolic function, and improving protein homeostasis. Spermidine plays an important role in many cellular functions, such as maintaining DNA stability, replicating DNA into RNA, and preventing cell death, and is active in combating a variety of age-related diseases, such as cardiovascular disease and neurodegeneration. Spermidine was originally extracted from semen and is a polyamine that is particularly abundant in sperm, but the most important sources of spermidine are plants, such as wheat germ and soybeans.

Wheat Germ Extract Spermidine Powder offered by Green Spring Technology is a natural plant extract ingredient, the extraction solution is ethanol and water without any solvent residue. Spermidine powder is fine and water-soluble. From the raw material wheat germ to the finished product spermidine powder, the whole production process of Green Spring is controlled and traceable, and the detection of various pollutants meets the global standards.

Established in 2000, Green Spring Technology is a professional plant extracts supplier, dedicated to providing natural, safe, and organic plant extracts to our customers. All of the products we offer implement the highest international industry standards, complying with EU EC396, EU 2023/915 standards, and the highest solvent residue standards. All products are traceable, and each product from source to finished product has detailed testing, and production reports to ensure that every aspect of the production process can be controlled and verified. We have passed Halal, Kosher, COSMOS, BRC, IFS, FDA, ISO, and many other certifications. We can provide authoritative third-party inspection reports.

Specification: 

Regulation:

It conforms to EU regulations.

Benefits:

Anti-Aging

Spermidine is a naturally occurring polyamine that stimulates cellular autophagy, and as we age, the amount of spermidine in our bodies decreases. Scientists have observed that increased intake of spermidine is associated with a decrease in total mortality from cardiovascular disease and cancer.

Since the Dutch scientist Levenhuk discovered the existence of spermidine in 1678, scientists have published several studies on spermidine in NATURE and SCIENCE. It has been found that spermidine resists aging mainly through the following ways: increasing cellular autophagy, promoting lipid metabolism, and regulating cell growth and death processes. Cellular autophagy is the main function of spermidine, that is, for the removal of waste substances in the cells, purifying the cellular living environment, so that the human body is in a clean state, playing a positive role in slowing down the aging process. In addition to cellular autophagy, spermidine also induces mitochondrial autophagy, thereby promoting mitochondrial health.

Spermidine can also open up multiple anti-aging channels, on the one hand, inhibit mTOR (excessive activity will promote cancer and accelerate aging), and on the other hand, activate AMPK (an important longevity channel that reduces inflammation and burns fat), so as to achieve a full range of anti-aging. In nematode experiments, supplementation with spermidine to activate AMPK was able to extend lifespan by 15%.

Anti-cancer

Several studies have shown that spermidine supplementation can reduce tumourigenesis in mice, such as reducing the incidence of visible skin tumors in aged female mice, slowing the growth of colorectal tumors in mice; and reducing the incidence of hepatocellular carcinoma in mice with severe liver fibrosis. It has also been found that spermidine enhances anti-tumour immune responses.

Cardiovascular Protection

In 2016, Atherosclerosis published research confirming that spermidine reduces lipid accumulation in atherosclerotic plaques. In the same year, Nature Medicine published a study confirming that spermidine reduces cardiac hypertrophy and improves diastolic function, leading to cardioprotective effects and prolonging the lifespan of mice.

Improvement of Alzheimer's Disease

Spermidine intake is beneficial to human memory function. Professor Reinhart's team in Australia found that spermidine treatment can improve cognitive function in the elderly. The study used a multicentre, double-blind design to enroll 85 elderly people in six nursing homes, who were randomly divided into two groups and given different doses of spermidine powder. Cognitive functions were assessed by a memory test, and the participants were divided into four groups: no dementia, mild dementia, moderate dementia, and severe dementia, blood samples were collected to assess the concentration of spermidine in their blood. The results showed that the concentration of spermine was significantly correlated with cognitive function in the group without dementia and that the cognitive level of the elderly with mild to moderate dementia was significantly improved after the intake of high doses of spermine.

Improving Metabolic Disease

In 2014, a study in The European Journal of Pathology showed that supplementation with spermidine improved glucose utilization and significantly reduced body weight in obese mice, and in 2017, a study published in Cell Death & Disease, a sub-publication of Nature, showed that Spermidine reduces weight gain due to high-calorie diet and improves obesity-related symptoms in mice.

Applications:

For Health Products:

Wheat germ extract spermidine powder can protect DNA from oxidative damage by free radicals, and has been used in health products.