Urolithin A Powder 98%

Urolithin A Powder 98%

CAS No.:1143-70-0

Specification:98%

Testing Method:HPLC

Appearance:Off-white to Yellow Fine Powder

Pesticide Residue:Comply with (EC) No 396/2005 Standard

  • Description
  • Data Sheet
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  • What is Urolithin A Powder?


    Urolithin A is a compound produced by the metabolism of ellagitannin-rich foods (e.g. pomegranates, raspberries, etc.) in the intestinal flora. It was first discovered in 2005 by a team of scientists from Cerdá and confirmed to be a metabolite of the gut microbiota. Uricetin A is believed to have anti-inflammatory, anti-aging, antioxidant, and mitochondrial autophagy-inducing effects, and can cross the blood-brain barrier.

     

    Green Spring Technology supplies Urolithin A Powder 98%, which is a high purity, low impurity, off-white to light yellow powder, and has been used in the field of health products and cosmetics.

     

    Founded in 2000, Green Spring Technology is a leading biotechnology company in China. It has a strong scientific research team, a strict production management team, a professional and efficient production team, and a professional sales team. Green Spring has 8 certifications and 7 patents, and its products are sold in more than 62 countries, serving more than 2,450 customers, and are well received.


    Specification: 

       

    Product Name

    Urolithin A Powder

    CAS No.

    1143-70-0

    Assay

    98%

    Testing Method

    HPLC

    Appearance

    Off-white to Yellow Fine Powder

    Pesticide Residue

    Comply with (EC) No 396/2005 Standard


    Regulation:


    It conforms to EU regulations.

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    Benefits:


    Anti-Aging

    In a study published in August 2023 in the top scientific journal Nature, urolithin A was found to restore the function of haematopoietic stem cells in aging mice (18 months of age and older) to the level of young mice at 8-12 weeks of age. The researchers further elaborated that urolithin A promotes autophagy and regeneration of mitochondria, which enhances the viability of haematopoietic stem cells, making them more "youthful", which in turn improves immunity.

     

    Antioxidant

    Compared to other metabolites, urolithin A displays potent anti-inflammatory, antioxidant, and anti-aging properties. It fights oxidation through multiple pathways: for example, it can directly scavenge free radicals and reduce oxidative stress; for example, it activates the Nrf2 antioxidant pathway and enhances cellular antioxidant defenses, and then, for example, it inhibits the activity of enzymes involved in the generation of reactive oxygen species and protects cells from oxidative damage.

     

    Weight Loss

    Studies have shown that urolithin A prevents diet-induced obesity and metabolic dysfunction without adverse effects. Urocitin A increases triiodothyronine (T3) levels in adipose tissue, promotes body heat production in brown adipose tissue, and induces browning of white adipose tissue, resulting in increased energy expenditure and a reduction in fat cells and fat mass.

     

    Improving the Liver

    In a 2020 study, scientists found that urolithin A can improve liver and kidney damage in mice through mechanisms that attenuate oxidative stress, inflammatory responses, and apoptosis. In the liver, for example, ALT (alanine aminotransferase) and AST (aspartate aminotransferase) levels in the treated group (using three different doses of urolithin), showed a significant recovery compared to the model group (untreated), suggesting that urushiol A improves liver function and liver injury. In the kidney histomorphology it can be observed that the group with the highest dose of urushiol surprisingly tended to improve more than the control group (normal group), which reflects the efficacy of urushiol treatment, in improving kidney injury.

     

    Regulates Intestinal Flora

    Urocitin A increases the expression of tight junction proteins, which improves intestinal flora, reduces markers of inflammation, and restores the colon barrier function, relieving colonic inflammation. In addition, dark yellow and black colored urolithin A products often contain organic impurities. High purity urolithin A products are usually pale yellow.


    Applications:


    For Healthcare Products:

    As a natural compound with a wide range of biological activities, urolithin A powder has a promising market application and shows potential in some areas. The anti-aging properties of urolithin A give it potential applications in anti-aging nutraceuticals, helping to slow down the cellular aging process, improving mitochondrial function by stimulating mitochondrial autophagy, helping to remove aged and damaged mitochondria from cells, and promoting the growth of healthy mitochondria. Given its anti-inflammatory and antioxidant properties, urolithin A can be included in supplements that promote cardiovascular health. For athletes and fitness enthusiasts, urolithin A powder can be used as a nutritional supplement to enhance muscle performance and recovery.


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