Reduced Coenzyme Q10 (Ubiquinol) Powder CAS 992-78-9

What is Reduced Coenzyme Q10 (Ubiquinol ) Powder?

Reduced coenzyme Q10 (CoQ10H2) is the reduced state of coenzyme Q10. In the human body, coenzyme Q10 can transfer electrons from receptors such as NADH and FADH2 to oxygen in a multistep reaction that culminates in the generation of ATP and the concomitant reduction of coenzyme Q10.

The main feature of Reduced Coenzyme Q10 is its extreme antioxidant capacity. It can protect biomolecules in cells from oxidative damage by trapping free radicals and inhibiting oxidative stress. In addition, reduced coenzyme Q10 can strengthen the electron transfer capacity of the mitochondrial respiratory chain, which can promote the production of ATP, thus improving cell viability. To date, clinical trials have shown that reduced coenzyme Q10 is more readily absorbed by the body than oxidized coenzyme Q10.

Green Spring Technology provides pharmaceutical grade 85%Reduced Coenzyme Q10 (Ubiquinol ) Powder CAS 992-78-9, it has excellent stability, good solubility, and absorption.

At 25°C/60% RH in open air at 25°C/60% RH for 4 weeks, the content of reduced coenzyme Q10 in the market decreased by 6%, while Green Spring’s Reduced Coenzyme Q10 (Ubiquinol ) Powder content decreased by only2% reduction. It performs better stability. It displays an obviously increased solubility (38.3 times in simulated gastric fluid and 12.6 times in simulated intestinal fluid). It increases absorption (4.5 times in AUC and 2-4 times in Cmax) compared with normal coenzyme Q10.

Founded in 2000, Green Spring Technology is dedicated to providing our customers with natural, safe and organic plant extracts. All the products we offer are manufactured to the highest international industry standards, complying with EU EC396, EU 2023/915 and the highest solvent residue standards. We have excellent R&D team, experienced production team and can customize various standardized extracts. It has been certified by Halal, Kosher, COSMOS, BRC, IFS, FDA, ISO and many more.

Specification: 

Regulation:

It conforms to EU regulations.

Benefits:

Scavenging Free Radicals

Coenzyme Q10 exists in both reduced and oxidized states, with reduced coenzyme Q10 (Ubiquinol) being easily oxidized, preventing lipid and protein peroxidation, scavenging free radicals, and reducing oxidative stress. Oxidative stress is a negative effect produced in the body by free radicals and is a major contributor to aging and disease. Coenzyme Q10 is a potent antioxidant and free radical scavenger that slows the harmful effects of oxidative stress.

Coenzyme Q10 can improve the bioavailability of the skin, condition the skin, increase the concentration of keratinized cells, improve the antioxidant capacity of skin cells, and inhibit skin aging to achieve a therapeutic effect on skin diseases such as dermatitis, acne, bedsores, skin ulcers and so on. Coenzyme Q10 also promotes epithelial cell generation and granulation tissue benignization, prevents scar formation, and promotes scar repair. Inhibits the activity of phosphotyrosine, preventing melanin as well as dark spot production. Reduces the depth of wrinkles and improves skin dullness. Increases the concentration of hyaluronic acid and improves the water content of the skin. It is effective in improving dull skin tone, reducing wrinkles, and restoring skin's original smoothness, elasticity, and moisturizing properties.

Enhancement of Human Immunity

As early as 1970, some studies reported that the administration of coenzyme Q10 to rats could increase the vitality of immune cells to kill bacteria, and increase the antibody response, stimulate the increase of immunoglobulin and the number of antibodies.

Nikbakht et al. investigated that the number of neutral leukocytes in the blood plasma of male athletes was significantly reduced when they were administered with coenzyme Q10 after successive competitions, and thus concluded that coenzyme Q10 was beneficial to the protection of the immune system of athletes and strengthened the immunity of the body. This suggests that coenzyme Q10 can help to protect the immune system of athletes and enhance the immunity of the body. For normal people, oral coenzyme Q10 can improve fatigue and enhance the vitality of the body after overexertion.

Recent studies have shown that coenzyme Q10, as a non-specific immune enhancer, can play a better role in improving the body's immunity and anti-tumor, etc., and has a certain degree of clinical efficacy in advanced metastatic cancer.

Enhance Cardiac Motility

Coenzyme Q10 is one of the most important substances in the human body, and its content in the heart muscle is very high. When it is deficient, it will cause insufficient function of the heart, resulting in poor blood circulation and reduced work capacity of the heart. The main effects of coenzyme Q10 on the myocardium are to promote cellular oxidative phosphorylation, improve myocardial energy metabolism, and reduce ischemic damage to the myocardium. It can increase the blood output of the heart, improve the chronic congestion state and anti-arrhythmia, etc., which can protect the myocardium, improve cardiac function, and provide enough energy for the myocardium.

Clinical studies have shown that more than 75% of patients with heart disease experience significant improvement in their condition after taking Coenzyme Q10. Coenzyme Q10 is a metabolic activator that activates cellular respiration, providing sufficient oxygen and energy to cardiomyocytes and brain cells to keep them in good health, thus preventing cardiovascular and cerebrovascular events.

Regulation of Blood Lipids

Lipid-lowering drug statins will block the body's autonomous synthesis of coenzyme Q10 while lowering blood lipids. Therefore, people with high blood fat must take coenzyme Q10 when taking statin drugs to better play the role of lipid-lowering. Coenzyme Q10 can reduce the harmful LDL content, prevent LDL from penetrating deep into the endothelial cell gap through the endothelial cells, reduce the formation of lipids in the inner wall of the arteries, and prevent lipids from forming atherosclerotic plaques in the inner lining of the blood vessels, as well as improve the activity of high-density lipoproteins, and timely removal of garbage, toxins and plaques formed in the inner wall of the blood vessels, regulating blood lipids and preventing atherosclerosis formation.

Applications:

In Pharmaceutical:

Coenzyme Q10 (Ubiquinol) is also widely used in the field of medicine, where it is used to treat a variety of diseases such as heart disease, cancer, and neurodegenerative diseases. Studies have shown that Coenzyme Q10 can help improve heart health, reduce fatigue, and boost immunity.

Currently, the coenzyme Q10-based pharmaceutical preparations approved for marketing in China are tablets, capsules, soft capsules, injections, etc., which are prescription drugs. The specifications of coenzyme Q10 solid preparations (tablets, capsules, soft capsules) are mainly 5mg, 10mg, and 15mg, which can be used for the adjuvant treatment of cardiovascular diseases (e.g., viral myocarditis, chronic cardiac insufficiency, etc.), hepatitis (e.g., viral hepatitis, subacute hepatitis of severe type, chronic active hepatitis, etc.), and the comprehensive treatment of cancer (to alleviate certain adverse reactions induced by radiotherapy, chemotherapy, etc.). (to alleviate certain adverse reactions caused by radiotherapy, chemotherapy, etc.).

In Cosmetics:

The strong antioxidant effect of Coenzyme Q10 (ubiquinone) has led to its increasing attention in the cosmetic market. If added to creams, it can remove free radicals in the surface skin cells, making the skin less wrinkled and appear smoother and more delicate; in the deeper skin cells, it can maintain the skin's elasticity. In addition, Coenzyme Q10 can also be used in the care of hair, nails, mouth and so on.

In the Food Field:

Coenzyme Q10 powder is also added to certain foods such as nutritional supplements, beverages, breads, and candies to increase their nutritional value. It is also used to improve the antioxidant properties of foods, which helps prevent spoilage and decay.