99% PQQ (Pyrroloquinoline Quinone) Bulk Powder

What is PQQ Powder?

PQQ, also known as pyrroloquinoline quinone, 4,5-dihydro-4,5-dioxo-1H-pyrrolo [2,3-f] quinoline-2,7,9-tricarboxylic acid, molecular formula C14H6N2O8, molecular weight 330.206.

The initial source of PQQ in nature was probably synthesized by Gram-negative bacteria using glutamate and tyrosine as substrates. PQQ in plant tissues may be derived from biosynthesis by inter-root microorganisms, which in turn enter animals through the food chain. The production of pyrroloquinoline quinone by microbial or chemical synthesis has been industrialized.

PQQ (Pyrroloquinoline Quinone) supports mitochondrial growth and development, stimulates rapid growth of human cells, and possesses powerful antioxidant properties that can help scavenge free radicals and reduce cellular damage. It has a powerful role in cardiovascular health, brain health, metabolic function health, etc. It can mainly help physical recovery and anti-fatigue.

Green Spring Technology supplies 99% PQQ (Pyrroloquinoline Quinone) Bulk Powder , stable, high content, fine powder, good solubility, no pesticide residue, and low solvent residue. Green Spring has passed Halal, Kosher, COSMOS, BRC, IFS, FDA, ISO and many other certifications. Green Spring has always been committed to providing our customers with natural, safe and organic plant extracts. All the products we offer are implemented to the highest international industry standards. Authoritative third party test reports are available.

Specification:

Regulations:

It conforms to EU regulations.

Benefits:

Growth Promoting Factors

Poor mitochondrial physical and mental health is associated with a variety of common diseases, including IQ decline, heart disease, diabetics and cancer. Controlled studies in mice fed with PQQ have shown that PQQ powder not only promotes mitochondrial growth, but also prolongs the life of the active components of mitochondrial biosynthesis, avoids oxidation of vital air, and enhances energy utilization. However, in tissue cell experiments, pyrroloquinoline quinone powder was able to stimulate human fibroblast DNA production, copying and cellular metabolism when PQQ concentration values were relatively low.

Researchers have analyzed that improving mitochondrial physical and mental health is likely to be the reason behind many of PQQ's physical and mental health benefits, such as improved kinetic energy, memory and sleep quality.

Neuroprotection

In an experiment analyzing the association between pyrroloquinoline quinone powder and stroke and cervical cord injury, it was found that PQQ powder could reduce neuronal death, and at the same time effectively promote the functional recovery of rat spinal nerves after hemisection injury.PQQ significantly reversed the reduction of Bax/Bcl-2 caused by β-amyloid convergence and suppressed the cleavage of Caspase-3. Pyrroloquinoline quinone powder suppressed the establishment of amyloid and its cytotoxicity of shortened α-synuclein and maintained neuronal cells damaged by the toxic side effects of β-amyloid convergence. PQQ powder inhibits the establishment of amyloid and the cytotoxicity of shortened α-synuclein, and maintains neuronal cells damaged by the toxic side effects of β-amyloid aggregation.

An exploration of 41 Japanese older adults tested the autonomic impact of PQQ. Over 12 weeks of days, study subjects were split into 2 groups, each taking 20mg of PQQ or a placebo effect. Cognitive tests illustrated that pyrroloquinoline quinone powder boosted memory and concentration, and brain scans uncovered elevated blood volume.

Antioxidant

The antioxidant effect of pyrroloquinoline quinone(PQQ) powder could be significantly noticed in the test of PQQ poultry and livestock. It was found that PQQ can inhibit the establishment of sodium peroxynitrite, block SIN-1-induced ATP deprivation, and eliminate superoxide anion to prevent the nitration reaction of bovine serum albumin. In addition, PQQ blocked the neurotoxin 6-methylcholine from causing ozone and reduced the cytotoxicity of 6-methyldopamine.

Applications:

For Health Products:

Pyrroloquinoline quinone (PQQ) powder can be used as a therapeutic aid in heart disease, neurological disorders, liver protection, etc. The nutritional and efficacy value of PQQ  has been recognized and it has become a popular mitochondrial supplement in foreign countries. PQQ has been widely used in brain health, energy supplementation, cardiovascular health, beauty and many other areas.PQQ powder is not only used alone but also combined with traditional mitochondrial supplements such as Coenzyme Q10, Lipoic Acid, Taurine, L-Carnitine, and so on.

In the Food Field:

In recent years, as awareness continues to grow, PQQ has achieved the most comprehensive efficacy certification and has been classified as a high safety dietary supplement in the United States and the European Union.

United States: Pyrroloquinoline quinone (PQQ) has obtained GRAS certification from the U.S. Food and Drug Administration (FDA), and can be used as an ingredient in food products such as energy drinks, sports drinks, electrolyte drinks, and bottled water; in 2009, the first PQQ dietary supplement was approved in the United States for the first time, and the supplement ingredient is the sodium salt of PQQ (PQQ-2Na+) since PQQ is slightly soluble in water.

EU: On 13 August 2018, the European Commission (ESFA) published Regulation (EU) 2018/1122 approving pyrroloquinoline quinone sodium salt as a novel food. Following Regulation (EU) 2015/2283 of the European Parliament and of the Council, the Commission amended the Annex to Implementing Regulation (EU) 2017/2470 for the use of pyrroloquinoline quinone sodium salt as a dietary supplement as defined in Directive 2002/46/EC for the target population of adults excluding pregnant and breastfeeding women, with a maximum dosage of pyrroloquinoline quinone sodium salt of 20mg/day.