Pure Melatonin Powder

What is Pure Melatonin Powder?

Melatonin is a hormone secreted by the pineal gland in the human body, which regulates the function of the human nervous system and many aspects of physiological activity. Melatonin belongs to indole heterocyclic compounds, and its chemical name is N-acetyl-5-methoxytryptamine.

Melatonin is an important part of the biological clock and sleep-wake cycle in the human body, which can help people fall asleep, improve sleep quality, anti-aging, and protect blood vessels. Its secretion is affected by light and darkness, decreasing during the day when exposed to sunlight, increasing at night, peaking, and then gradually decreasing until morning, a process that helps people fall asleep and stay asleep.

Greenspring Technology supplies Pure Melatonin Powder, which is a white crystalline powder with purity greater than 99.5%, usually used as raw material for health care products.

Green Spring Technology is a leading biotechnology company in China, that has been devoted to researching, developing and supplying high-quality plant extracts, natural nutraceutical ingredients, food ingredients and cosmetic ingredients. It organizes its production in strict accordance with ISO, HACCP and other quality standards. It has passed Halal, Kosher, COSMOS, BRC, IFS, FDA, ISO and many other certifications.

Specification: 

Regulation:

It conforms to EU regulations.

Benefits:

Regulation of Circadian Rhythms

Melatonin regulates circadian rhythms, such as sleep-wake rhythms, neuroendocrine rhythms, or body temperature cycles, through its action on MT1 and MT2 receptors. Melatonin intake can lead to fatigue, sleepiness, and shortened sleep latency. Circadian rhythm disruption is associated with sleep disorders and impaired health.

For example, children with a wide range of developmental, neuropsychiatric, and health problems often exhibit melatonin deficiency. When circadian rhythms are restored, behavior, mood, development, intellectual functioning, health, and even seizure control may improve. Notably, according to several studies, circadian rhythms are important for typical (normal) neurodevelopment, and circadian deficits inhibit neurogenesis in animal models.

Anti-aging

Melatonin protects cell structure, prevents DNA damage, and reduces peroxide levels in the body by scavenging free radicals, antioxidizing, and inhibiting lipid peroxidation. A study by Russel et al. found that melatonin protects against DNA damage caused by safrole (a carcinogen that damages DNA through the release of free radicals) by up to 99% in a dose-response relationship. -response relationship.

Melatonin has a significant antagonistic effect on tissue damage caused by peroxidation and free radicals generated by exogenous toxicants. Melatonin also reduces LPO content in the brain. Its effects were essentially the same in different regions of the brain, such as the cerebral cortex, cerebellum, hippocampus, hypothalamus, and striatum, and all showed a dose-dependent relationship. However, different strains of rats such as Sprague-Dawlay and Wistar rats have different sensitivities to melatonin.

Antioxidant

Melatonin has a strong antioxidant effect that scavenges free radicals in the body and reduces damage to cells and tissues caused by oxidative stress. Free radicals are one of the most important factors contributing to cellular aging and the development of diseases. By inhibiting lipid peroxidation and protein over-oxidation, melatonin protects cellular structure and prevents DNA damage, thus slowing down the aging process. In addition, melatonin enhances cellular activity and promotes skin metabolism, helping to maintain the skin's youthful appearance.

Immunomodulation

Yann et al. studied the regulatory effect of melatonin on the immunity of H22 hepatocellular carcinoma mice and found that it could increase the CD4+CD8+ value of loaded mice, synergize with IL-2 to increase the number of peripheral blood lymphocytes and eosinophils, enhance the NK and LAK activity of splenocytes, and promote the induction of IL-2.

They also investigated the regulatory effect of melatonin on the macrophage function of H22 hepatocellular carcinoma mice and found that the killing activity of macrophages and the induction of IL-1 were significantly increased after the injection. It was found that after injection, the killing activity of macrophages and the induction of IL-1 increased significantly, indicating a selective regulation of macrophage function. Kathleen et al. (1994) found that melatonin has the function of activating human monocytes and inducing their cytotoxicity and IL-1 secretion.

Applications:

For Healthcare Products:

Melatonin's healthcare functions of regulating immune function, anti-tumor, anti-aging, etc. are showing its strong vitality, and it has great potential as a new type of health food. So far, China has included melatonin in the catalog of health food ingredients as “sleep-improving” health food. The U.S. FDA (Food and Drug Administration) believes that melatonin can be used as a common dietary supplement.