Pterostilbene Powder 99%

What is Pterostilbene?

Pterostilbene is a chemical component contained in red sandalwood, but scientists have found the existence of pterostilbene in other plants, but because it was first found in rosewood, it was named pterostilbene. Pterostilbene is white or off-white powder crystals, has a rich medicinal value, belongs to the blood exhaust products in the antifungal active ingredients, for cancer, hypertension, high blood pressure, high blood fat treatment have a certain effect. Recently, researchers have mastered the industrial synthesis method of pterostilbene.

As a trans-stilbene analog, pterostilbene is a methylated derivative of resveratrol, which has a variety of biological activities such as antioxidant, anti-tumor, lipid-lowering and bacteriostatic, and is more bioavailable and stable than resveratrol.

Green Spring Technology supplies Pterostilbene Powder 99%, which utilizes new liposome technology to realize pterostilbene powder nano-embedding, which effectively improves the low bioavailability and poor solubility of pterostilbene, and significantly improves its transdermal absorption effect and compatibility. The solubility of this pterostilbene powder is good because the liposome technology effectively improves the problem of low solubility of pterostilbene; the stability is excellent, the liposome technology has a good protective effect, and the stability of pterostilbene after encapsulation is significantly improved.

Founded in 2000, Green Spring Technology is a technology-driven high-tech enterprise dedicated to the research and development, production, and sales of natural plant extracts. It has a perfect quality management system and organizes production according to ISO, HACCP, and other quality standards. Green Spring has 7 certificates and 7 patents, and its products are sold in more than 62 countries worldwide, serving more than 2450 customers and are well received. We have passed Halal, Kosher, COSMOS, BRC, IFS, FDA, ISO, and many other certifications. 

Specification: 

Regulations:

It conforms to EU regulations.

Benefits:

Antioxidant

Pterostilbene has been shown to help reduce free radical damage. When compared to tetrahydrocurcumin, photoglycopyrrolidine, and vitamin C, astragalus has the strongest oxygen radical uptake; and has a strong ability to inhibit DPPH free radicals, which suggests a superb antioxidant effect. In published studies, pterostilbene has been found to display direct antioxidant effects while also modulating antioxidant enzymes and defense systems throughout the body. No known botanical ingredient has surpassed this to date.

Inhibition of Melanin

Pterostilbene is a unique autophagy inducer, that can effectively induce cytoprotective autophagy in human umbilical vein endothelial cells by rapidly increasing intracellular calcium concentration and AMPKa1 activation, and thus inhibiting mTOR, a negative regulator of autophagy. Pterostilbene plays an inhibitory role against melanogenesis by down-regulating proteins involved in α-MSH-triggered B16-F10 cells and induces resistance through autophagy to melanogenesis.

Spot Removal

In the assay experiments for the efficacy of spot removal, the untreated cells had obvious black spots; while the cells were treated with 0.55 μg/ml of pterostilbenes (90%), used every 3 days for 9 days, and eventually the black spots disappeared, indicating that it has a good effect of spot removal.

Whitening

Pterostilbene has excellent melanin and complexin inhibiting effects. Studies have shown that it inhibits melanogenesis, melanocyte dendrites and melanosome transport via the cAMP/PKA/CREB pathway. Its half inhibitory concentration IC50 value for tyrosinase is significantly better than that of common whitening ingredients such as vitamin C and arbutin, and only slightly lower than that of photoglycoside. When compared with whitening ingredients such as glycyrrhizin, tretinoin and vitamin C, pterostilbene has the most significant melanin inhibiting effect. Not only that, pterostilbene can also promote cell autophagy and effectively metabolize melanin and lipofuscin that have already been generated in the skin, so its whitening speed is more rapid than that of common whitening ingredients.

Protects against UV Damage

Studies have shown that pterostilbene can express antioxidant enzymes and has good UVB protective efficacy. In cellular experiments, 30 μg/mL of pterostilbene can reduce half of the cytotoxic damage caused by UVB; and a low concentration of 4 μmol/L of pterostilbene pretreatment can inhibit the DNA damage of skin cells by UVA irradiation. In addition, the use of the sun protection factor (SPF value) test in human experiments revealed that the SPF value of the cream containing 0.4% pterostilbene was 6.2, which demonstrated the effect of pterostilbene as a natural sunscreen.

Anti-Inflammatory

Through the regulation of the Nrf2 pathway, pterostilbene can effectively inhibit the expression of inflammatory factors such as COX-2, PGE2, and NO, demonstrating excellent anti-inflammatory effects. Meanwhile, pterostilbene is also able to reduce intracellular inflammatory responses and reactive oxygen species (ROS) levels and inhibit neutrophil activation, inflammatory mediator production, and endothelial cell apoptosis.

Applications:

In Cosmetics:

According to domestic and international research reports, pterostilbene possesses a variety of skincare effects such as whitening, antioxidant, anti-inflammatory, anti-glycation, defense against UV damage as well as firming and anti-wrinkles, and is considered one of the most all-round whitening and anti-aging cosmetic ingredients. Pterostilbene powder has been used as an ingredient in various high-end cosmetic formulations.