Milk Thistle Extract Powder Silymarin 80% UV

What is Milk Thistle Extract Powder?

Milk thistle extract powder is made from the dried fruit of Silybum marianum G. crushed, extracted, concentrated, and spray-dried into powder. The active ingredients of milk thistle extract powder are silydianin, isosilydianin, dehydrosilydianin, silydianin, silychristin, silychristin polymer, and cinnamic acid, myristic acid, palmitoleic acid, and arachidic acid.

Milk thistle extract powder helps in liver detoxification and can also be used to manage chronic liver diseases. It activates the regeneration of liver proteins and restores the activity of liver cells damaged by alcohol and viruses. It also scavenges free radicals, maintains the permeability of liver cell membranes, and reduces liver damage caused by toxins. It protects people whose liver is injured by long-term alcohol consumption and who suffer from acute and chronic hepatitis, fatty liver, cirrhosis, and toxic liver damage.

Green Spring Technology supplies Silymarin Extract with uniform and meticulous powder, stable properties, good solubility, and low moisture content, which can prolong the storage period. Good water solubility, all water soluble, dissolved in water clarified and translucent, no precipitation; maintain the original taste and colour of raw materials.

Green Spring Technology has a set of systematic quality management systems, strictly implements the quality management system, and organises the production according to ISO, HACCP and other quality standards. Strictly complying with the European Pharmacopoeia, American Pharmacopoeia, and Japanese Pharmacopoeia, the powdered silymarin extracts we supply have pesticide residues, heavy metals and solvent residues following international standards. We can provide authoritative third-party test reports.

Specification:

Regulations:

It conforms to EU regulations.

Benefits:

Antiviral Activity

Silymarin and its derivatives can produce potent antiviral activity by acting at multiple points in the viral life cycle. For example, the most researched of all is the hepatitis C virus HCV, where silymarin not only enhances the antiviral effects of the JAK-STAT signaling pathway.

It can also inhibit NS5B polymerase activity and inhibit the transcription of nuclear factor NF-κB, thus blocking the virus from entering cells and replicating and spreading. Against the influenza A virus, silymarin can inhibit viral RNA synthesis and viral replication in the late stage of infection. Against dengue virus, both silymarin and its derivatives have a very strong affinity for the viral non-structural protein NS4B, and thus can also be used as anti-dengue virus targets for treatment.

Anti-Inflammatory Activity

The enzyme 5-lipoxygenase (5-LOX) has been strongly implicated in many inflammatory conditions and cancers, and since 5-LOX is expressed in various tissues and cells of the body, it is now widely believed that 5-LOX is one of the causes of the inflammatory cascade. Silymarin, a milk thistle extract ingredient, happens to act on 5-LOX, thereby reducing the production of the inflammatory mediators leukotrienes and lipoxins and reducing the inflammatory response.

Antioxidant

Milk thistle extract reduces cellular damage caused by oxygen free radicals such as ROS, and superoxide anion. Especially in the face of environmental stresses such as drugs, silymarin increases the production of glutathione and superoxide dismutase. In addition, prolonged high sugar intake, although pleasurable, may induce the generation of large amounts of superoxide to cause damage to glomerular podocytes, and silymarin can do this in two ways. One is to enhance the activity of antioxidant enzymes in the kidneys, such as catalase and glutathione peroxidase, etc., and the other is to inhibit NADPH oxidase, thus achieving the effect of protecting the kidneys.

Anti-fibrotic

Numerous studies have shown that milk thistle extract can inhibit NF-kB activity while blocking other protein kinase-like signaling pathways. Supplementation with silymarin inhibits pre-collagen production in activated hepatic stellate cells, thus demonstrating significant anti-fibrotic efficacy. But while there have been many successful trials of this type, most of them are still being conducted in animals such as rats and baboons.

Liver Protection

Milk thistle extract has a protective effect against liver damage caused by carbon tetrachloride, galactosamine, alcohol, and other hepatotoxins. Studies have shown that oral administration of silymarin significantly alters the structure of the intestinal flora. It greatly promotes the colonization of relevant flora capable of synthesizing vitamin B12, while the level of triglycerides in human serum is significantly negatively correlated with the level of VB12. It increases the level of fatty acid degradation by the liver, thus improving the accumulation of liver fat from high-fat dietary levels.

Anti-Cardiovascular Disease

By investigating the effect of milk thistle extract on hang high cholesterol and LDL oxidation in mice fed with polyunsaturated fatty acid and a small amount of saturated fatty acid food containing silymarin, and in control of mice fed with polyunsaturated fatty acid and a small amount of saturated fatty acid food, serum cholesterol levels were significantly reduced in the former, with a decrease in gross VLDL and an increase in HDL I-C, suggesting that silymarin improves the anti-LDL capacity.

Applications:

In Pharmaceutical:

Milk thistle extract powder is used as an ingredient in the treatment of liver diseases such as hepatitis and cirrhosis. It is also used to improve digestion, lower cholesterol and promote bile production. Milk thistle extract is often used in oral or injectable preparations.

In the Food Field:

Due to the rich nutritional components of milk thistle extract powder, such as flavonoids, coumarins, and ellagic acid, it is often used in health foods, functional beverages, and healthy grains.

In Cosmetics:

Milk thistle extract has antioxidant, anti-inflammatory, and moisturizing effects, making it often used in cosmetics such as skincare, makeup, and shampoo.

For Feed Product:

Milk thistle extract powder can be used for the treatment of animal liver diseases, such as pig hepatitis and bovine jaundice as a raw material.