Berberine HCL 97%

What is Berberine HCL 97%?

Berberine hydrochloride is an isoquinoline alkaloid with various activities extracted from the rhizomes of plants such as Huanglian, Phellodendron Bark, and Sanguisorbia. It has the functions of clearing heat, detoxification, and fire detoxification, and is widely used in Chinese medicine. Its initial application in clinical practice was mainly to exert an antibacterial effect as an active ingredient in the treatment of gastrointestinal inflammation.

It has also shown good efficacy in the treatment of diarrhea caused by dysentery and irritable bowel syndrome. It has been widely used as an over-the-counter medicine against dysentery. Berberine hydrochloride has also been shown to be effective in regulating blood sugar and lipid metabolism, preventing atherosclerosis, resisting cardiac arrhythmia, inhibiting tumor cell proliferation, and acting as an antiviral.

Green Spring Technology supplies Berberine HCL 97%, which is a fine yellow powder extracted from the root of Phellodendron chinense Schneid and purified, mainly used as raw material for medicine and health care products. The production of Berberine Hydrochloride Powder is controlled and traceable from raw material to finished product. We strictly monitor the pesticide residues of raw materials, and the testing of various pollutants meets global standards.

Founded in 2000, Green Spring Technology is a leading biotechnology company in China. It strictly implements a quality management system and organizes production following ISO, HACCP, and other quality standards. The products implement the highest standards in the international industry, complying with EU EC396, EU 2023/915 and the highest solvent residue standards. Green Spring has obtained Halal, Kosher, COSMOS, BRC, IFS, FDA, ISO9001, ISO22000 and many other certifications. Authoritative third-party test reports are available.

Specification:  

Regulation:

It conforms to EU regulations.

Benefits:

Antibacterial

Berberine hydrochloride has an inhibitory effect on a wide range of bacteria, especially on Gram-positive and Gram-negative bacteria. It can inhibit bacterial growth at low concentrations and kill bacteria at high concentrations. For staphylococcus, streptococcus, pneumococcus, Vibrio cholerae, Bacillus anthracis, and other common pathogenic bacteria, berberine hydrochloride tablets have a strong antibacterial effect.

Regulation of Blood Sugar

In recent years, clinical studies have shown that berberine (Berberine) can stimulate insulin secretion, improve insulin resistance, and at the same time, it can counteract the hormone that raises blood glucose, which has a perfect regulating effect on blood glucose. In a paper titled "Progress in the study of the mechanism of action of berberine on glycolipid metabolism", researchers found that berberine (Berberine) can effectively regulate blood sugar. Many experiments, especially animal experiments, have also confirmed this pattern. Therefore, Berberine can not only be used to treat diarrhea, but also has the effect of regulating blood sugar.

Improving Insulin Resistance

Insulin resistance is an important risk factor for obesity and type 2 diabetes. Berberine Hydrochloride improves insulin resistance and promotes normal insulin function, helping the body use glucose more efficiently and reducing fat synthesis and storage.

Promotes Adipose Tissue Browning

Berberine hydrochloride may also promote the browning of adipose tissue by activating the SIRT1-FGF21 axis of action. Brown adipose tissue has higher metabolic activity and can burn more energy, thus contributing to body fat reduction and weight loss.

Beneficial for Cholecystitis

Chronic cholecystitis is a chronic inflammatory response disease, mostly caused by chronic bacterial infection, chemical damage, stone irritation, and recurrent acute cholecystitis. Berberine hydrochloride is the main active ingredient in Berberis. In addition to its well-known antibacterial effect, berberine hydrochloride has an anti-platelet aggregation effect, which improves the blood supply to the gallbladder mucosa. Previous studies have found that TNF-α levels in the serum of patients with chronic cholecystitis are significantly higher than those of healthy volunteers and that anti-inflammatory treatment can dramatically reduce TNF-α levels.

LEP can regulate the inflammatory response and oxidative stress of the body and can activate the NF-κB pathway to participate in the inflammatory response. The study of Tang Jun et al. showed that berberine hydrochloride tablets combined with fennel trisulfide tablets in the treatment of chronic cholecystitis in elderly patients can improve clinical symptoms and reduce the levels of TNF-α and LEP. Its application in the treatment of chronic cholecystitis has clinical significance.

Applications:

In Pharmaceutical:

It has been found that berberine hydrochloride powder and its derivatives have good performance in the treatment of hypoglycemia, hypolipidemia, anti-atherosclerosis, psychiatric disorders, immune system disorders, Alzheimer's disease, tumors, and many other aspects. New pharmacological effects of berberine hydrochloride are gradually being discovered, and the discovery of these new effects provides new possibilities for the future clinical application of berberine hydrochloride.