Vitamin K2 MK7 Powder

Vitamin K2 MK7 Powder 0.5%

Product Name:Vitamin K2 MK7 Powder 0.5%

Assay:0.5%

Testing Method:HPLC

Appearance:Light Yellow Powder

Pesticide Residue:Comply with (EC) No 396/2005 Standard

  • Description
  • Data Sheet
  • Certificate
  • What is Vitamin K2 MK7 Powder ?


    Vitamin K2 MK-7 is a fat-soluble derivative of vitamin K. It is one of the more active forms of the vitamin K family and has important physiological functions. There are synthetic and fermented sources, the best source of fermented MK-7 is natto, MK-7 has higher bioavailability, longer half-life, and stronger anti-osteoporotic activity.

     

    Vitamin K2 MK7 can regulate bone extracellular matrix mineralization by stimulating osteoblast differentiation. Up-regulates bone marker gene expression, inhibits osteoclastogenesis, promotes bone formation, and inhibits bone resorption. It has the effect of preventing and controlling osteoporosis.

     

    Green Spring Technology supplies Vitamin K2 MK7 Powder 0.5% is a natural, all-trans configuration of Vitamin K2 MK7 Powder produced through a fermentation process using a high-purity, natural strain of Bacillus subtilis natto that grows under strictly controlled conditions, following rules that are stricter than the ICH guideline standards. It is unadulterated, highly pure, and stable, and it minimizes cross-reactivity with other ingredients or excipients in formulations. It has no impurities, high purity, good stability, and can minimize cross-reactivity with other ingredients or excipients in the formulation, thus meeting the quality requirements in all aspects.

     

    Green Spring Technology organizes its production in strict accordance with ISO, HACCP and other quality standards, and organizes its production in accordance with ISO, HACCP and other quality standards. Green Spring has passed Halal, Kosher, COSMOS, BRC, IFS, FDA, ISO and many other certifications. Authoritative third-party test reports are available.

     

    Specification:

     

    Product Name

    Vitamin K2 MK7 Powder

    CAS No. 

    2124-57-4

    Assay

    0.5%

    Testing Method

    HPLC

    Appearance

    Light Yellow Powder

    Pesticide Residue

    Comply with (EC) No 396/2005 Standard


    Regulations:


    It conforms to EU regulations.

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    Benefits:


    Anti-Osteoporosis

    The mechanism of action of vitamin K2 MK7 powder anti-osteoporosis is not only through the vitamin K-dependent protein gamma-carboxylation pathway but also by stimulating osteoblast differentiation and regulating bone extracellular matrix mineralization. Up-regulating bone marker gene expression, inhibiting osteoclastogenesis. Promote bone formation and reduce bone resorption, thus preventing and controlling osteoporosis.

     

    Vitamin K2 is the key to the gamma-carboxylation of osteocalcin. Uncarboxylated osteocalcin cannot bind hydroxyapatite in bone tissue, and carboxylated osteocalcin can bind calcium ions in hydroxyapatite crystals, thus exerting its role in regulating the composition of bone extracellular matrix and the size and shape of hydroxyapatite crystals.

     

    Vitamin K2 MK7 Powder can affect the proliferation and differentiation of osteoblasts and prevent osteoblast apoptosis. It can inhibit Fass-mediated apoptosis of osteoblasts in a dose-dependent manner and can improve osteoblast function more effectively.

     

    Inhibits Bone Resorption by Osteoclasts

    Vitamin K2 MK7 powder can directly or indirectly inhibit osteoclast formation by interfering with RANKL expression and up-regulating OPG expression in osteoclast precursors; in osteoblast medium, vitamin K2 reduces the proliferation of tartrate-resistant acid phosphatase-positive (TRAP+) cells and decreases their activity; vitamin K2 induces bone resorption factors [e.g. PGE2, IL1α and 1,25(OH)2D3] to inhibit bone resorption in a dose-dependent manner.

     

    Helps Fight Cancer

    A German study suggests that vitamin K2 may be effective in preventing prostate cancer; "Men taking the highest dose of K2 had about a 50 percent chance of developing prostate cancer." A study funded by the U.S. National Cancer Institute suggests vitamin K2 may help reduce the risk of developing non-Hodgkin's lymphoma. "Researchers found that people with the highest vitamin K2 intake had a 45 percent lower risk of developing this cancer than those with the lowest vitamin K2 intake." The European Prospective Investigation into Cancer study found that a high intake of vitamin K2 (but not vitamin K1) reduces the risk of cancer, indicating a 30 percent lower risk of cancer death.

     

    Helps Reduce the Incidence of Coronary Heart Disease

    A study of 4,807 people without cardiovascular disease followed for seven years showed that a high intake of vitamin K2 was able to reduce the incidence of coronary heart disease compared to a low vitamin K2MK7 intake. Another study showed that every 10μg increase in vitamin K2 intake reduced the incidence of coronary heart disease by 9%.

     

    Slowing the Progression of Coronary Artery Calcification

    Results of a randomized, double-blind controlled trial involving 180 patients with coronary artery disease suggest that supplementation with vitamin K2 MK-7 powder slows the progression of coronary artery calcification in patients with coronary artery disease.


    Applications:


    For Health Products:

    Vitamin K2 MK-7 is a long-chain vitamin K2 found in fermented foods that has better bioavailability than MK-4 and is considered to be the longer-lasting, safer, and more potent form of vitamin K2 with greater healthcare potential. It plays an important role in many ways. Vitamin K2 MK7 Powder is not only good for bone health, but it also helps prevent atherosclerosis and keep blood vessels healthy.

     


  • Vitamin K2 MK7 Powder 0.5% COA

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