Pyrroloquinoline Quinone Disodium Powder 98% Bulk

What is Pyrroloquinoline Quinone Disodium Powder?

Pyrroloquinoline quinone disodium, also known as pyrroloquinoline quinoline quinone disodium salt, chemical formula C14H6N2O8, is a coenzyme of oxidoreductase. Its unique o-benzoquinone structure endows it with many different physiological properties from other coenzymes and also gives it different physiological effects.

Pyrroloquinoline quinone disodium is made from 6-amino-5-methoxy-1H-indole-2-carboxylic acid ethyl ester and 2-oxopentenedioic acid dimethyl ester by coupling ring-forming reaction, formation of quinoline ring, oxidation reaction, ester hydrolysis reaction, and refining.

Disodium pyrroloquinoline quinone occurs naturally in the soil can be taken up by plants and can be found in a wide variety of plants and animals. In addition, some bacteria in fermented foods and beverages produce PQQ. parsley and peppers in vegetables, kiwi and papaya in fruits, green and oolong teas in beverages, tofu contains about 30 ng/g, and natto beans contain a high level of 61 ng/g of PQQ. PQQ is found in all tissues of the human body and is an essential growth factor for development.

Green Spring Technology supplies Pyrroloquinoline Quinone Disodium Powder 98% Bulk with high content and good stability. Green Spring has a systematic quality management system and organizes production in strict accordance with ISO, HACCP, and other quality standards. Green Spring has established a perfect traceability system, all products can be traced, and each product from the source to the finished product has a detailed test, and production report, to ensure that every link in the production process can be controlled and checked. Green Spring has an independent testing laboratory and advanced testing instruments to ensure product safety and compliance.

Specification:

Regulations:

It conforms to EU regulations.

Benefits:

Improvement of Mitochondria

Pyrroloquinoline quinone disodium helps to optimize energy production and has a powerful ability to replenish mitochondrial energy and mitochondrial autophagy; it also stimulates mitochondrial biosynthesis, resulting in increased synthesis and enhanced function, which in turn improves mitochondrial utilization. In 2013, researchers at the University of California Nutrition Center administered pyrroloquinoline quinone disodium powder supplementation to 10 people (5 men and 5 women), and after 76 hours to test its effects, the experimental group taking pyrroloquinoline quinone disodium powder had an increase of about 163 percent in fresh mitochondria in their cells, as measured by blood and urine tests.

Immune Enhancement

Pyrroloquinoline quinone disodium powder is the most potent biologically active substance ever discovered, capable of stimulating the growth of the body's B-cells, T-cells, and other lymphocytes, causing them to produce antibodies, thus improving the body's immune function in general.

Antioxidant

Pyrroloquinoline quinone disodium powder is a very powerful antioxidant and has the unique benefit of being able to produce near-continuous catalytic cycling, i.e., the ability to carry out repetitive oxidation and reduction reactions, to a greater extent. Pyrroloquinoline quinone disodium is capable of 20,000 catalytic conversions, whereas vitamin C provides only 4 catalytic conversions, meaning that disodium pyrroloquinoline quinone provides 5,000 times more functional antioxidant protection than vitamin C.

Helps Brain Cognition

Pyrroloquinoline quinone disodium ameliorates neuronal damage caused by the oxygen-glucose deprivation model, reduces alterations in the content of Nysted's vesicles caused by factor D-galactose treatment, and inhibits neuronal degeneration. It has a debilitating effect on nerve damage caused by β-amyloid and helps promote the secretion of neurotrophic factors. Disodium pyrroloquinoline quinone also inhibits the formation of peroxynitrite, potentially oxidising the redox site of the N-methyl-D-aspartate (NMDA) receptor. Thereby reducing the activity of the NMDA receptor. Also, can act as a potent antioxidant to protect mitochondrial lipids and proteins and has been shown to protect mitochondrial function from oxidative damage and promote the generation of new mitochondria and neurons. In addition, pyrroloquinoline quinone disodium has significant memory retention and dementia prevention effects.

Detoxification

Japanese scientists have found that pyrroloquinoline quinone disodium powder can speed up the oxidation of acetaldehyde to acetic acid to reduce the level of acetaldehyde in the body, which is expected to reduce the toxic damage caused by alcohol consumption to the liver. Scholars have found that oral consumption of pyrroloquinoline quinone disodium can effectively reduce blood lead, brain lead, liver lead levels, and does not cause the loss of beneficial metal elements zinc and copper in the body.

Anti-inflammatory

Pyrroloquinoline quinone disodium has antioxidant properties that can help neutralize harmful free radicals and prevent cell damage and inflammation. Studies have shown that after just three days, supplementation with pyrroloquinoline quinone disodium powder significantly reduces many markers of inflammation.

Improvement of Reproductive Function

Pyrroloquinoline quinone disodium powder improves reproductive function in animals, inhibits ovarian aging with age, and regulates the environment for follicle maturation and ovulation.

Beneficial for Cardiovascular Health

Pyrroloquinoline quinone disodium can inhibit the production of ROS in myocardial cells and the decrease in mitochondrial membrane potential, thereby reducing myocardial cell death. To protect the heart, prevent myocardial ischemia and myocardial infarction, etc.

Protecting the Liver

Pyrroloquinoline quinone disodium can protect the liver against alcohol and carbon tetrachloride induced liver damage, as well as TAA induced liver fibrosis.

Activate Longevity Genes

According to authoritative journals such as the Journal of Cell Science and PNAS, pyrroloquinoline quinone disodium can activate two longevity related genes, SIRT1 and SIRT3.

Applications:

For Health Products:

In 2012, Health Canada (HC) approved Pyrroloquinoline Quinone Disodium(PQQ) as a natural health food. At present, the common PQQ supplement products on the market are mainly aimed at brain health, sleep aid, energy supplementation, oral beauty, and pregnancy assistance, often combined with coenzyme Q10 and GABA, Ginkgo biloba leaf extract, phosphatidylserine (PS) and other raw materials are used in combination.

At present, the combination of pyrroloquinoline quinone disodium powder and anti-aging raw material NMN has become a classic, promoting mitochondrial energy supply and mitochondrial regeneration. Pyrroloquinoline quinone disodium powder, as a mitochondrial targeted nutrient, promotes mitochondrial biogenesis and functional health and enhances human energy metabolism.