Pyrroloquinoline Quinone Bulk Powder

What is Pyrroloquinoline Quinone Powder?

Pyrroloquinoline quinone (PQQ for short), a new water-soluble vitamin with strong redox activity, is an oxidoreductase cofactor found in some microorganisms, plants, and animal tissues.PQQ also participates in a wide range of redox reactions and influences the physiological and metabolic processes of the human body by acting as a cofactor and mediating a series of cellular and molecular biochemical reactions.PQQ is widely found in nature, including many animals, plants microorganisms, and some common foods. Pyrroloquinoline quinone can enhance the redox reaction ability of cells, thus helping the body to better utilize energy, enhance metabolism, resist fatigue, improve concentration and memory, etc. PQQ also has a strong antioxidant ability, which helps to protect against harmful free radicals and protects the human body's health and life activities.

The Pyrroloquinoline Quinone Powder Bulk supplied by Green Spring Technology is produced through microbial fermentation and synthesis method, which is less polluting to the environment, has a mild reaction, and safer production process. This pyrroloquinoline quinone powder has high content and good stability. From raw material to product, the whole production process of Green Spring is controllable and traceable, and the testing of various pollutants meets global standards.

Green Spring is a leading supplier of plant extracts in China, it was established in 2000 and is a certified supplier. It can supply more than 210 kinds of products and export to 62 countries. It has a systematic quality management system, strictly implements the quality management system, and organizes production according to ISO, HACCP, and other quality standards. Greenspring has passed Halal, Kosher, COSMOS, BRC, IFS, FDA, ISO, and many other certifications. With an excellent R&D team and experienced production team, Green Spring can customize various standard extracts as well as proportional extracts.

Specification: 

Regulation:

It conforms to EU regulations.

Benefits:

Nutrition and Protection of Nerves

Pyrroloquinoline quinone(PQQ) plays a prominent role in nutrition and nerve protection. Nerve growth factor (NGF) plays an important regulatory role in the development, growth, regeneration, and functional expression of central and peripheral neurons. Early research found that PQQ can promote the generation of NGF. Pyrroloquinoline quinone can promote the synthesis and secretion of NGF by Schwann cells, indicating that this effect of PQQ occurs at the pre-transcriptional level. Pyrroloquinoline quinone can significantly reduce neurobehavioral defects and infarct size, indicating its potential value in preventing and treating stroke. The mechanism of PQQ inhibiting oxidative stress leading to neuronal death is related to increasing the level of DJ-1-reducing protein in the brain.

Alleviate Inflammation

Pyrroloquinoline quinone can significantly inhibit the inflammatory response and protect the body tissues. Rheumatoid arthritis is caused by the body's immune cells mistaking joint cells for foreign invaders and then attacking them. The body then releases inflammatory factors and enzymes that damage the articular cartilage and even the entire joint. The researchers found that PQQ inhibited the release of inflammatory factors from fibroblast-like synovial cells and prevented the activation of nuclear transcription factors.

The researchers also found that pyrroloquinoline quinone powder reduced the activity of specific enzymes (such as matrix metalloproteinases) that break down ear collagen in the joints. Nitric oxide is one of the biological indicators of inflammation, and it is supposed to reduce inflammation and dilate vascular nerves. However, under certain circumstances, excess nitric oxide can lead to inflammation in order to stimulate mitochondrial biosynthesis, resulting in an increase in their number and function, thus improving energy utilization.PQQ can regulate mitochondria through four pathways: Disorders. This test shows that pyrroloquinoline quinone also has the effect of reducing collagenolytic enzymes and nitric oxide.

Increase the Number of Mitochondria

Mitochondria are important sites for cells to undergo oxidative phosphorylation and generate energy, serving as the power factory of cells. More than 95% of the energy for body movement comes from mitochondria. Pyrroloquinoline quinone increases the number and function of mitochondria by regulating the biosynthesis of oxidative enzyme proliferators activating receptor factors. PQQ can stimulate the cyclic adenosine phosphate binding protein to regulate mitochondrial biosynthesis. Pyrroloquinoline quinone (PQQ) increases the synthesis of mitochondrial transcription factors through gene regulation and nuclear respiratory factor (NRF) action, achieving regulation of mitochondria.

Enhance metabolism, enhance the role of immunity

Pyrroloquinoline quinone can stimulate the growth of human cells, especially activate human B-cells, and T-cells, so that it produces antibodies to improve the immune function of the body.PQQ can reduce fatigue, reduce anxiety, reduce LDL cholesterol levels, improve sleep quality, and prolong sleep time.

Applications:

For Health Products:

Pyrroloquinoline quinone powder has a variety of health benefits, including antioxidant effects, promoting energy metabolism, protecting the nervous system, improving sleep quality, enhancing immunity, promoting cardiovascular health, and promoting liver health. Therefore, PQQ is widely used in the field of nutraceuticals. Pyrroloquinoline quinone powder(PQQ) is regulated as a "Generally Recognised As Safe (GRAS)" substance in the United States, and can be used as an ingredient in energy drinks, sports drinks, electrolyte drinks, and other food products; and in the EU and Canada, it is used as a dietary supplement or natural health food.

In Pharmaceutical:

Pyrroloquinoline quinone powder is used abroad in anti-glycation and brain health pharmaceutical research, respectively.