D Panthenol Liquid

What is D Panthenol Liquid?

D panthenol, also known as provitamin B5, is a co active substance of pantothenic acid and a precursor of coenzyme A. Compared with pantothenic acid, D-panthenol has more stable properties, with a molecular weight of only 205, and can effectively penetrate into the stratum corneum. Quickly converted to pantothenic acid, which is converted into coenzyme A in the body. Coenzyme A is a cofactor of various enzyme reaction pathways in the body, which participates in cell energy metabolism and provides energy for the body's life activities. In addition, it also participates in the metabolism of various key components in the skin.

D panthenol is an important vitamin drug that can protect the mucous membranes and luster on the skin surface, preventing the occurrence of diseases. As a nutritional supplement, D panthenol is widely used in the pharmaceutical, food, and cosmetics industries, with specific formulations such as oral liquid, eye drops, compound vitamin injections, shampoo, mousse, moisturizers, etc. As a member of the water-soluble vitamin family, D panthenol can play a good role in skin moisturizing and hair care.

Green Spring Technology supplies high-purity D panthenol liquid, which is free of impurities. Solvent residues and pesticide residues comply with European Union and US Pharmacopoeia standards. From raw materials to products, the production process of Green Spring is controllable and traceable, and the detection of various pollutants meets global standards. We can provide authoritative third-party testing reports.

Specification: 

Regulations:

It conforms to EU regulations.

Benefits:

Long Lasting Moisturizing Effect

D Panthenol Long-Term Moisturizing Mechanism: The intercellular lipids in the stratum corneum are important structures for maintaining skin barrier function. The latest research has found that the intercellular lipid arrangement in the stratum corneum of dry skin is different, and it is in a rigid environment with poor fluidity. D panthenol itself contains hydroxyl groups, which have hygroscopic and water retaining properties. Simultaneously promoting lipid synthesis, increasing the fluidity of lipid molecules and keratin microfilaments. Improving the rigid environment between keratinocytes helps maintain healthy skin barrier function.

The clinical research results show that the use of cream containing D panthenol liquid on healthy skin can effectively increase the moisture content of the stratum corneum, and there is a certain dose effect relationship; In addition, after the surfactant SLES destroys the skin barrier function, the use of panthenol containing cream can effectively reduce transdermal water loss (TEWL) and improve the skin barrier function.

Soothing Sensitive Skin

The soothing effect of D panthenol mainly comes from two aspects. On the one hand, D-panthenol can protect against oxidative stress damage. Under the influence of internal and external stress factors, cells will produce reactive oxygen species free radicals. When the cell's ability to clear free radicals is insufficient, the accumulated free radicals will have adverse effects on skin health and aging.

D panthenol can reduce the production of reactive oxygen species in skin cells, while upregulating the skin's own antioxidant mechanisms, including inducing the expression of more antioxidant factors - heme oxygenase-1 (HO-1) in skin cells, thereby improving the skin's antioxidant capacity. On the other hand, panthenol can reduce inflammatory response. After stimulating keratinocytes with capsaicin, the release of inflammatory factors IL-6 and IL-8 is significantly increased. However, after panthenol treatment, it can inhibit the release of inflammatory factors and thus alleviate the inflammatory response and relieve it.

Repair Skin Damage

The research results indicate that after treating the laser injury model with D panthenol liquid, the expression of the marker Ki67 for keratinocyte proliferation increases. This indicates that more keratinocytes enter a proliferative state, promoting epidermal regeneration. At the same time, the expression of Filaggrin, an important marker of keratinocyte differentiation and barrier function, also increased, indicating the promotion of skin barrier repair. The expression effect of D-panthenol on KI67 and silk fibroin.

The results show that the laser wound diameter shrinks faster after the use of cream containing 5% panthenol after carbon dioxide dot matrix laser surgery, which continues to be better than the control cream. At the same time, the re epithelialization score was also significantly higher than that of the control cream, suggesting that in the laser injury model, panthenol showed the role of promoting the proliferation and differentiation of epidermal cells and accelerating the repair of laser induced epidermal damage.

Applications:

In Cosmetics:

D panthenol liquid used in skin care products can stimulate cell division and proliferation, promote normal keratinization, wound healing, anti-inflammatory, moisturizing, and have a preventive effect on intense sunlight moisturizing. A new study in 2019 showed that panthenol promotes wound healing faster than mineral oil and can also improve scars. It is used in hair products such as shampoo and conditioner, which can nourish, moisturize, repair hair, reduce entanglement, increase hair density, improve hair luster, and make hair shiny and oily.

In the Food Field:

As the same metabolic process as vitamin B5 in organisms, D panthenol liquid can be used as a nutritional supplement and enhancer to promote the metabolism of proteins, fats, and sugars in the human body.